South America Cruises
Amazon rainforests to Patagonia glaciers
South America offers the most ecologically and culturally diverse cruising on the planet — from Amazon River expedition cruises through the jungle canopy to dramatic Patagonia sailings past glaciers and penguin colonies at the southern tip of the world. Buenos Aires, Rio de Janeiro, and Lima add world-class urban culture to the mix.
Highlights
- Amazon River cruises deep into the rainforest
- Cape Horn and the Drake Passage
- Patagonia: Torres del Paine, Perito Moreno Glacier
- Rio de Janeiro's iconic entry under Christ the Redeemer
- Machu Picchu land extension from Lima
Top Ports of Call
Cruise Lines We Recommend
Frequently Asked Questions
What South American cruise is most popular?
The Buenos Aires to Santiago (or reverse) itinerary through Patagonia is the most popular, typically 14–16 days. It includes Falkland Islands, Cape Horn, Chilean Fjords, and glaciers — one of the most scenic cruise routes in the world.
Can I cruise the Amazon River?
Yes — ocean ships sail the lower Amazon, docking in Manaus (Brazil) deep in the rainforest. Expedition ships can go further upriver. Amazon cruises are typically combined with a Brazil coastal sailing or Caribbean itinerary.
Is South America safe for cruise passengers?
Port areas visited by cruise ships are generally well-patrolled and safe. We always recommend booking shore excursions through the ship for security and convenience, particularly in larger ports like Rio de Janeiro and Cartagena.
Ready to Cruise South America?
Pam Jaffe plans every South America cruise with firsthand expertise — from cabin selection to shore excursions. Everything is completely free.